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KMID : 0425120000380040251
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Parasites, Hosts and Diseases
2000 Volume.38 No. 4 p.251 ~ p.256
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Seroepidemiological study of Toxoplasma gondii infection in the rural area Okcheon-gun, Korea
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Young-Ha LEE/Young-Ha LEE
Hyung-Jun NOH/Ok-Sun HWANG/Sang-Keol LEE/Dae-Whan SHIN
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Abstract
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There have been some reports about the prevalence of anti-Toxoplasma gondii antibody among Koreans, and most of all data were taken from patients visiting hospitals. However, the epidemiological data of the community-based study in Korea are rare. This study was performed to evaluate the seroprevalence of toxoplasmosis among the inhabitants of the rural area Okcheon-gun, Korea. A total of 1,109 serum samples (499 males, 610 females) were examined for the IgG antibodies by ELISA. To set up the cut-off point for ELISA, we used a commercial latex agglutination (LA) kit. The sensitivity and specificity of ELISA against LA test were 89.5%, and 98.6% respectively. Among 1,109 sera, 6.9% showed seropositivity by ELISA. The positive rates of males and females were 6.0% and 7.2%, respectively. However, there were no significant differences between sexes. Comparing the age groups, the highest seropositive rate showed in the seventies or higher, and their rates had a tendency to increase with age (0.05 < p < 0.3). These results revealed that the seroprevalence of toxoplasmosis in rural inhabitants is similar to previous reports in Korea; however we need further investigation to clarify the prevalence of toxoplasmosis in the general population.
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KEYWORD
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Toxoplasma gondii, toxoplasmosis, seroepidemiology, latex agglutination, ELISA, Korea,
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