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KMID : 0607520080160010047
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Korean Journal of Psychosomatic Medicine
2008 Volume.16 No. 1 p.47 ~ p.51
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Association Study of a Norepinephrine Transporter T-182C Polymorphism and Anxiety-Related Traits
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Lim Se-Won
Kim Kye-Hyun
Woo Hee-Yeon
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Abstract
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Objectives : The aim of this study was to investigate the relationship between the norepinephrine(NET) transporter T-182C polymorphism and anxiety-related traits in Korean adolescent females.
Methods : One hundred sixty-nine Korean adolescent females were tested for the NET T-182C polymorphism by PCR based methods; anxiety-related traits were evaluated using the anxiety sensitivity index(ASI) and the trait form of the Spielberg State-Trait Anxiety inventory(STAI-T).
Results : Scores of anxiety related traits were not different between genotypes. Comparison between T allele carries and non carriers revealed no significant difference.
Conclusion : These findings suggest that the NET T-182C polymorphism is not associated with anxiety-related traits in Korean female adolescents.
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KEYWORD
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Anxiety, Anxiet sensitivity, Polymorphism, Norepinephrine transporter
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