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KMID : 0608520080140010085
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Korean Journal of Oriental Medicine
2008 Volume.14 No. 1 p.85 ~ p.89
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Nonlinear analysis of cardiotonic effect of acupuncture treatment on heart rate variability assessed by 24-hour Holter monitoring
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Oh Dal-Seok
Lee Jeon
Kim Jong-Yeol
Choi Sun-Mi
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Abstract
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This study is to investigate cardiotonic effect of acupuncture on heart rate variability(HRV) analyzed by a nonlinear way(DFA, Detrended Fluctuation Analysis). It was designed as a randomized, single-blind, waiting list-controlled, cross-over study. We assessed heart rate and R-R intervals in Circadian electrocardiography with a Holter monitoring device for twelve hospitalized participants. The compatible analytical program, Zymed, was used for generating the signals of R-R intervals from 24 hour-ECG. In DFA analysis, we produced DFA alpha 1, alpha 2 parameters according to the process of Cygwin module of Linux server. We tested if there was any difference between HRV parameters using SPSS, a statistical package. There was no difference between acupuncture and no treatment group in DFA alpha 2 parameter {95% Confidence Interval (-)0.058 - 0.037, P = .565}. Two group all showed large intra-individual variations. Consequently, acupuncture treatment did not modulate the complexity of HRV in a DFA analysis. This study can be a rationale for acupuncture’s properties on cardiovascular and autonomic systems.
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KEYWORD
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heart rate variability, detrended fluctuation analysis, 24 hour ECG Holter monitoring
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