|
KMID : 0644120070200010114
|
|
Journal of Oriental Gynecology
2007 Volume.20 No. 1 p.114 ~ p.124
|
|
|
Vasodilatory Activities and Safety of the Water Extracts of Three Medicinal Remedy in Species of Insects
|
|
Kim Eun-Young
Rhyu Mee-Ra
Roh Jin-Ju
Kim Dong-Il
|
|
|
Abstract
|
|
|
Purpose:The pharmacological effects of medicinal remedies traditionally used in Asian countries for improving the blood circulation were examined on isolated rat thoracic aorta strips in organ baths.
Material and Methods : Each experimental medicine was consecutively extracted under reflux with water. Of three medicinal remedies . Hirudo(HI) having the strongest acute relaxant activity in endothelium-intact arteries, Tabanus(TA), Empoly ohaga(EO) were showing dose-dependent relaxant activity. Long-term relaxant effects were showed in Hirudo(HI) and Empoly ohaga(EO). In endothelium-injury test using carbachol, Hirudo(HI), Tabanus(TA) and Empoly of ohaga(EO) were not damaged to endothelium.
b>Conclusion: As a result of this study, the possibility that a part of medicinal remedy may contribute to the beneficial effects in blood circulation was proposed, but inter-individual variation has been observed. Also, further studies on the vasorelaxant effects of these remedies are still required
|
|
|
KEYWORD
|
|
|
vasorelaxant, Hirudo, Tabanus, Empoly ohaga
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|