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KMID : 0644120230360020055
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Journal of Oriental Gynecology
2023 Volume.36 No. 2 p.55 ~ p.68
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A Systematic Review and Meta-Analysis on the Effect of Guibi-tang for Postpartum Depression
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Kang Eun-Sol
Ahn Young-Tae
Kim Hyo-Jeong
Hyun Ji-Soo
Kang Jin-Young
Lee Yoon-Jae
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Abstract
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Objectives: The purpose of this study is to analyze the effectiveness of Guibi-tang that are used for postpartum depression.
Methods: We searched on five databases [Korean studies Information Service (KISS), Oriental medicine advanced searching integrated system (OASIS), The Cochrane Library, PubMed, and China national knowledge infrastructure (CNKI)] with keywords for Postpartum depression (English, Korean, and Chinese) and evaluated the risk of bias. Meta-analysis was performed on the selected studies.
Results: 8 potentially relevant articles were retrieved for further evaluation. There was evidence that Guibi-tang compared with Western medicine was significantly higher rate in total effect rate (RR 1.20, 95% CI 1.04, 1.39, p=0.01). Also, the combined therapeutic effects of Guibi-tang and Psychological intervention compared with Psychological intervention were statistically significant in total effect rate (RR 1.14, 95% CI 1.05, 1.24, p=0.002). And they showed improvement on scores of HAMD (Hamilton depression scale, HAMD) and SF-36 (36-Item short form health survey, SF-36).
Conclusion: Guibi-tang appears to be more effective compared to Western medicine in the treatment of postpartum depression. The combination Guibi-tang and Psychological intervention was more effective than psychological intervention alone treated for postpartum depression. However, since unclear risk of bias, the result of this study should be considered carefully. Further clinical trials should be carried out in order to academical clinical progress regarding treatment of Postpartum Depression.
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KEYWORD
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Postpartum Depression, Herbal Medicine, Guibi-tang, Korean Medicine, Chinese Medicine
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