KMID : 0665220010140020099
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Korean Journal of Food and Nutrition 2001 Volume.14 No. 2 p.99 ~ p.105
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Immunoregulative Action of Ethyl Alcohol Fraction of Cervus nippon
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Abstract
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Immunoregulative action of 70% ethyl alcohol fraction of Cervus nippon was investigated in vitro. The fraction enhanced the proliferation of thymocytes and the population of CD4^+CD8^- single-positive. cells in thymocytes. CN-E enhanced [Ca^2+]_i, the production of TNF-¥á and IL-1¥â, and phagocytosis in peritoneal macrophages. The fraction did not induce the proliferation of splenocytes and DNA fragmentation in thymocytes. These results indicate that 70% ethyl alcohol fraction of Cervus nippon regulates immunological action by stimulating murine thymocytes and macrophages.
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