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KMID : 0665220150280040594
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Korean Journal of Food and Nutrition
2015 Volume.28 No. 4 p.594 ~ p.601
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Antioxidant Activity and Cytotoxicity of Ethanol Extracts from Different Parts of Taraxacum coreanum Nakai cultivated in South Korea
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Park Myoung-Su
Jeong Bo-Reum
Bahk Gyung-Jin
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Abstract
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In the present study, the total content of polyphenols and flavonoids, the antioxidant activities, and cytotoxic effects of the ethanol extracts from different parts of Taraxacum coreanum Nakai were investigated for their use as functional foods. The extract yields of the flower, leaf, and root were 32.15±3.21%, 31.63±0.63%, and 27.48±2.47%, respectively. Total polyphenol and flavonoid content of the flower extract were 61.29±2.11 mg/g and 46.11±1.88 mg/g, respectively, which were much higher than those of any other plant parts. The antioxidant activities of the flower, leaf, and root extracts were 89.99±2.83%, 85.29±2.22%, and 37.88±2.34%, respectively, at a concentration of 1.0 mg/mL. Cell cytotoxicity effects of AGS (human gastric carcinoma), HCT116 (human colon carcinoma), and A549 (human pulmonary carcinoma) cells were the highest in the flower extract, with values of 62.85±4.63%, 69.89±3.44%, and 85.72±4.17%, respectively, at a concentration of 400 mg/kg. Both the antioxidant activities and cytotoxic effects of the ethanol extracts from all the parts of the T. coreanum Nakai increased dose-dependently. These results provide preliminary data for the development of T. coreanum Nakai as an edible functional food material.
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KEYWORD
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Taraxacum coreanum Nakai, antioxidant activity, anticancer activity, cytotoxicity
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