KMID : 0829320070100010001
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Korean Journal of Clinical Microbiology 2007 Volume.10 No. 1 p.1 ~ p.5
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RNAi: A Recent Revolutionary Tool for Understanding of Basic Biology
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Jung Dong-Kil
Cho Young-Suk Lee Won-Kil
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Abstract
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RNA interference (RNAi) is a gene-silencing technology by which small double-stranded RNAs are used to target the degradation of RNA with complementary sequence. RNAi is found in a wide variety of organisms (Caenorhabditis elegans, insects, plants, microorganisms and animals). With RNAi, we have harnessed the gene function to be explored, revolutionized our ability to perform large-scale genetic screens, and even therapeutic potential. (Korean J Clin Microbiol
2007;10:1-5)
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KEYWORD
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RNAi, Gene-silencing, Gene function, Therapeutic potential
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