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KMID : 08793198919890000529
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Annuals of Clinical Study - Seoul National Hospital
1989 Volume.1989 No. 0 p.529 ~ p.538
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Abstract
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Onset of schizophrenia after the age of 40 has been a controversial topic. Many of the studies had methodological short-comings, including problems in precisely dating the onset of schizophrenia. Late-onset schizophrenia is characterized by paranoid symptomatology, a high female: male ratio, an elevated prevalence of hearing loss and ocular pathology, schizoid or paranoid traits in premorbid personality,a tendency toward chronicity, and symptomatic improvement with neuroleptics. Family studies suggest that the prevalence of schizophrenia in relatives of late-onset schizophrenic probands is higher than that in re latives of earlier ?onset schizophenic probands. Studies of the course, biological associations, neuropsychological performance, and pharmacological characterization of late-onset schizophrenia are warranted.
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KEYWORD
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