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KMID : 0880420190200060894
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Korean Journal of Radiology
2019 Volume.20 No. 6 p.894 ~ p.908
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Multiparametric Functional Magnetic Resonance Imaging for Evaluating Renal Allograft Injury
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Yu Yuan Meng
Ni Qian Qian
Wang Zhen Jane
Chen Meng Lin
Zhang Long Jiang
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Abstract
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Kidney transplantation is the treatment of choice for patients with end-stage renal disease, as it extends survival and increases quality of life in these patients. However, chronic allograft injury continues to be a major problem, and leads to eventual graft loss. Early detection of allograft injury is essential for guiding appropriate intervention to delay or prevent irreversible damage. Several advanced MRI techniques can offer some important information regarding functional changes such as perfusion, diffusion, structural complexity, as well as oxygenation and fibrosis. This review highlights the potential of multiparametric MRI for noninvasive and comprehensive assessment of renal allograft injury.
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KEYWORD
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Multiparametric magnetic resonance imaging, Functional MRI, Kidney transplantation, Allograft fibrosis, Allograft dysfunction
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