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KMID : 0893319860010010047
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Journal of Environmental Toxicology
1986 Volume.1 No. 1 p.47 ~ p.54
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The Effect of Ginseng on the Immunotoxicity of Benzo(a)pyrene
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Ahn Young-Keun
Kim Zoo-Young
Shin Ha-Goung
Chung Jong-Gab
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Abstract
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The immunopotentiating effect of ethanol extract, butanol fraction and petroleum ether extract of Panax ginseng on the immunotoxicity of benzo(a)pyrene were investigated in mice. A single administration of benzo(a)pyrene induced an apparent but relatively transient reduction in HY titer, Arthus reaction, delayed type hypersensitivity, rosette forming cell and natural killer cell activity Ethanol extract very significantly restored HY titer, Arthus reaction. RFC and natural killer cell activity. Butanol fraction have no effect. But petroleum ether extract very significantly restored humoral and cellular immune response and especially natural killer cell activity.
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