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KMID : 0893319970120030061
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Journal of Environmental Toxicology
1997 Volume.12 No. 3 p.61 ~ p.66
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The Effect of Sulfur Dioxide by Burn out on Enzyme Activity and Lipid Content in Rats
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Kim Hae-Dong
Kim Byung-Hak
Ha Hun
Cho Soo-Yeul
Yoon Soo-Hong
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Abstract
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Recently, incidences of pulmonary-related diseases are increasing and natural ecosystem is destroyed year by year owing to air pollutions by industrial noxious gases such as sulfur dioxide and carbon dioxide, etc. Sulfur dioxide produced by oxidation of sulfur compounds is water soluble and causes several kinds of pulmonary diseases, damaging on plants and animals. This study was undertaken to investigate effects of acute exposure of rats to sulfur dioxide using biochemical parameters. The sAST (aspartate transaminase) activity was not significantly affected but sALT (alanine transaminase), sLDH (lactate dehydrogenase) and sALP (alkaline phosphatase) activities were significantly increased by acute sulfur dioxide gas exposure. Also sulfur dioxide gas treatment significantly diminished serum cholinesterase activity. The total lipid, triglyceride, total-, HDL- and LDL-cholesterol contents were significantly increased by sulfur dioxide gas exposures. But the body and liver weight were generally diminished in comparison with control group. Our results’ showed increased enzyme activities and lipid contents, but body and liver weight were all diminished by sulfur dioxide gas treatment.
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