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KMID : 0893320030180020101
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Journal of Environmental Toxicology
2003 Volume.18 No. 2 p.101 ~ p.109
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Distribution of Arsenic in Korean Human Tissues
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Lee Sang-Ki
Yang Ja-Youl
kim Ki-Wook
Lee Soo-Yeun
Kwon Tae-Jung
Yoo Young-Chan
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Abstract
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Humans are exposed to toxic element arsenic (As) from air, food and water The current study was performed to investigate the levels of arsenic in the internal organs (liver, kidney cortex, lung, cerebrum. abdominal muscle and abdominal skin) and to find out correlation with age and interrelationship between tissues in Korean human bodies who had lived in Seoul or Gyeonggi Province and Honam district. The tissues from 43 Korean cadavers were digested with microwave digestion system and arsenic was determined by inductively coupled plasma mass spectrometer (ICP-MS). The mean recovery percentages of arsenic In liver were about 80％ and artenic concentrations in human tissues were almost uniform. The mean level of arsenic in internal tissues were at follow ; liver 44.55625.199 ppb, kidney cortex 42.65222.082 pub, lung 31.020 17.504 ppb. cerebrum 35.703 22.191 ppb, muscle 43.41326.619 ppb and skin 42.10625.8,11 ppb. No significant difference was found in the levels of arsenic between sexes. Meanwhile significant differences between districts where they had lived were found in all tissues tested. The levels of arsenic in the tissues of cadavers who had lived in Seoul Gyeonggi Province were higher than those of Honam district. In addition a positive correlation between As concentration and age was observed only in the cerebrum (p < 0.05). A significantly high correlations between tissues were observed in all tissues tested. This result also shows that the distribution of arsenic is uniform in internal tissues.
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KEYWORD
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Korean, tissues, arsenic, distribution
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