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KMID : 0893320030180030219
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Journal of Environmental Toxicology
2003 Volume.18 No. 3 p.219 ~ p.224
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The Analysis of 1,4-Dioxane in Water Sample by Gas Chromatograph/Mass Spectrometer and Risk Assessment
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Hong Jee-Eun
Pyo Hee-Soo
Park Song-Ja
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Abstract
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1,4-Dioxane is used as a solvent for lacquers, paints, varnish removers, dye baths and printing compositions. And it is also used for detergent preparations, cosmetics, deodorants and fumigants. A method is described for the determination of 1,4-dioxane in water samples by GC/MS. The extraction recoveries were studied for some solvents and solvent volume ratio were investigated using r-butyl methyl ether (MTBE). Optimum condition was obtained by the liquid-liquid extraction using the 10 mL of MTBE for 10 mL of water. Method detection limit of 1,4-dioxane in the 20 mL of water samples was 0.05 ng/mL. It could be determined in the range of 0.24∼240 ng/mL in treated water, and in the range of 0.69∼81.9 ng/mL in raw water, respectively. Risk assessments with 1,4-dioxane exposure by drinking water ingestion were carried out. Based on the results of analysis, chronic daily intake of 1,4-dioxane was 2.2210-4/ mg/kg/day and excess cancer risk was calcu-lated to be 2.4410-6/.
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KEYWORD
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1,4-dioxane, drinking water, risk assessment
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