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KMID : 0900919920160020103
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Korean journal of Animal Reproduction
1992 Volume.16 No. 2 p.103 ~ p.107
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Studies on Artificial Control of Parturition in Korean Native Goats II. Serum Level of Progesterone Before and After Parturition by the Prostaglandin F_2alpha
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Yun Chang-Hyeon
Min Kwan-Sik
Oh Seok-Doo
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Abstract
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The present study was conducted to find out the changes of progesterone levels in pre and post partum by the PGF2alpha administration to control artificial parturition in Korean native goats. A total of 24 goats were offered for this experiment. The animals were divided into 4 goats per treatment by the administration time(142, 145 or 148 day of pregnancy). Blood samples were taken from jagular vein pre-post partum by the PGF2alpha intramuscular administration. The progesterone in serum was assayed by radioimmunoassay. The serum progesterone level in late-pregnant goats averaged 4.85pm0.55ng/ml, 4.05pm0.47ng/ml or 2.76pm0.25ng/ml on 142, 145 or 148 days of gestation. After the intramuscular injection with PGF2alpha for inducing parturition, it decreased remarkably to below 1.0ng/ml and to the base level(0.4~0.6ng/ml) at day 1 after parturition. And then this base level of progesterone was maintained until the final examination at 9 days of postpartum. No significant difference was found in the serum levels of progesterone between the doses treated for parturition induction. It was concluded that exogenous PGF2alpha, administrated intramuscularly, induced premature parturition with causing withdrawal of progesterone levels for triggering luteolysis.
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KEYWORD
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parturition, progesterone, PGF_2alpha
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