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KMID : 0927720100110010086
Korean Clinical Diabetes
2010 Volume.11 No. 1 p.86 ~ p.89
A Case of Hypoglycemia Caused by Orthosiphon in a Non-diabetic Man
Kim Jae-Hong

Cho Ho-Chan
Abstract
Hypoglycemia associated with the administration of drugs has been reported previously. Here, we report a case of hypoglycemia induced by Orthosiphon stamineus, which is a popular medicinal plant in Southeast Asia. A 27-year-old man was admitted to our hospital with tremor. He had ingested medication that included orlistat 360 mg and Orthosiphon stamineus extract 900 mg daily for more than 2 months to treat obesity. He had not experienced hypoglycemia prior to starting the above-mentioned medication and his symptoms disappeared rapidly with a carbohydrate-rich diet and discontinuation of the medication. Blood analysis after fasting provocation for 24 hours showed hypoglycemia (glucose level, 3.44 mmol/L) and simultaneous serum levels of insulin, C-peptide, and proinsulin were increased above normal to 17,835.45 pmol/L, 2.33 mmol/L, and 709 pmol/L, respectively. We report a case of hypoglycemia caused by Orthosiphon in a young non-diabetic man and propose that Orthosiphon stamineus extract, either alone or in combination with orlistat, might be beneficial for controlling glucose levels in diabetic patients.
KEYWORD
Hypoglycemia, Orthosiphon
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