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KMID : 1001920130540060528
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Journal of Korean Neurosurgical Society
2013 Volume.54 No. 6 p.528 ~ p.531
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Successful Treatment of Infantile Fibrosarcoma Spinal Metastasis by Chemotherapy and Stereotactic Hypofractionated Radiotherapy
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Lo Cheng-Hsiang
Cheng Shin-Nan
Lin Kuen-Tze
Jen Yee-Min
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Abstract
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We report a case of infantile fibrosarcoma in an 8-month-old boy manifested as a right-sided lower leg mass. Repeated local recurrence and distant metastasis were noted during the following three-year period. Whole body fluoro-deoxyglucose positron emission tomography scan revealed an asymptomatic metastasis involving the fourth lumbar vertebrae. The patient received chemotherapy (VAC regimen) with Cyberknife® stereotactic hypofractionated radiotherapy (26 Gy; 4 fractions). This treatment reduced tumor size by 23% without acute radiation toxicity even after 33 months. This case suggests that combining chemotherapy and this form of radiotherapy may be safe and effective against childhood spinal metastasis.
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KEYWORD
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Cyberknife®, Hypofractionated radiotherapy, Infantile fibrosarcoma, Spinal metastasis
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