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KMID : 1001920140560040334
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Journal of Korean Neurosurgical Society
2014 Volume.56 No. 4 p.334 ~ p.337
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Risk Factors Associated with Germinal Matrix-Intraventricular Hemorrhage in Preterm Neonates
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Kim Kwang-Ryeol
Jung Sang-Won
Kim Dong-Won
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Abstract
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Objective: The purpose of this study is to identify the risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) and the relationship of the severity of disease and prematurity.
Methods: A total of 168 premature neonates whose birth weight ≤1500 g or gestational age ≤34 weeks were examined by cranial ultrasound (CUS) for detection of GM-IVH among the babies admitted between January 2011 and December 2012 in our medical center neonatal intensive care unit. The babies were divided into two groups : GM-IVH and non-IVH. Clinical presentations, precipitating factors of the patients and maternal factors were analyzed.
Results: In univariate analysis, gestational age, birth weight, delivery method, presence of premature rupture of membrane (PROM) and level of sodium and glucose were statistically meaningful factors (p<0.05). But only two factors, gestational age and presence of patent ductus arteriosus (PDA) were statistically meaningful in multivariate logistic regression (p<0.05). Delivery method [normal vaginal delivery (NVD) to Caeserean section] was borderline significant (p<0.10).
Conclusion: Presence of PDA and gestational age were the important risk factors associated with development of GM-IVH.
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KEYWORD
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Germinal matrix-intraventricular hemorrhage, Gestational age, Ductus arteriosus, patent
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