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KMID : 1007520090180041042
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Food Science and Biotechnology
2009 Volume.18 No. 4 p.1042 ~ p.1045
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Antioxidant, Antimicrobial, and Cancer Cell Proliferative Inhibition Activities of Propolis
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Kang Ho-Jin
Ko Ki-Wan
Lee Ok-Hwan
Lee Boo-Yong
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Abstract
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A commercial propolis was investigated in terms of its antioxidant, antimicrobial, and antiproliferative activities.The contents of total phenol and flavonoid of propolis were 8.3 and 6.6 mg, respectively. The reducing power of the propolisincreased with concentration increasing. 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity was shown at82.70% in 1,000μg/mL of the propolis. 2,2’-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavengingeffect of antioxidant activity on the propolis was 35.64 g/sample. The propolis showed high antimicrobial activity againstBacillus cereus at all concentration of propolis. All of the cancer cell lines have 53-73% as effective growth inhibition. Theseresults showed that the commercial propolis has potential antioxidant, antimicrobial, and cancer cell proliferative inhibitionactivities thus, propolis can be applied to the functional food, pharmaceutical, and cosmetic industry.
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KEYWORD
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antioxidant, antimicrobial, cancer cell proliferative inhibition, propolis
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