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KMID : 1007520150240051901
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Food Science and Biotechnology
2015 Volume.24 No. 5 p.1901 ~ p.1905
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Artemisia annua L. Extract Ameliorates Galactose-Induced Cognitive Impairment in Mice
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Kim Mi-Hye
Seo Ji-Yeon
Kim Jong-Sang
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Abstract
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Our previous study showed that Artemisia annua L . extract (AAE) exerted antioxidative effect in a mouse model. Therefore, we hypothesized that AAE could also protect against oxidative stress-induced cognitive impairment, such as memory loss. Oral feeding of an AAE-containing diet resulted in weak yet significant protection from galactose-induced memory impairment and hippocampal damage in mice. The AAE-induced amelioration was likely associated with the ability of AAE to induce antioxidant enzymes.
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KEYWORD
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Artemisia annua, cognitive function, antioxidant enzymes, Morris water maze task
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