KMID : 1009020190170040559
|
|
Clinical Psychopharmacology and Neuroscience 2019 Volume.17 No. 4 p.559 ~ p.563
|
|
Efficacy of Asenapine in Schizophrenia Resistant to Clozapine Combined with Electroconvulsive Therapy: A Case Report
|
|
Ochi Shinichiro
Inoue Saori Yoshino Yuta Shimizu Hideaki Iga Jun-ichi Ueno Shu-ichi
|
|
Abstract
|
|
|
Schizophrenic patients resistant to antipsychotics are diagnosed as having treatment-refractory schizophrenia, and they are treated with clozapine. However, clozapine is sometimes combined with electroconvulsive therapy (ECT) if clozapine monotherapy fails. In this report, a severe treatment-refractory schizophrenic patient who did not respond to clozapine even with ECT, but who recovered with asenapine monotherapy, is presented. Asenapine, considered a serotonin spectrum dopamine modulator, is a new atypical antipsychotic with unique pharmacological features that is used not only for schizophrenia, but also for bipolar disorder. The unique features of asenapine may be effective for some treatment-refractory schizophrenic patients.
|
|
KEYWORD
|
|
Asenapine, Treatment-refractory schizophrenia, Clozapine, Electroconvulsive therapy, Suicide, Recurrence
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|