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KMID : 1011320160080010019
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Journal of Pharmacoepidemiology and Risk Management
2016 Volume.8 No. 1 p.19 ~ p.23
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Understanding and Management of Hypersensitivity Reactions to Iodinated Contrast Media
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Kang Dong-Yoon
Sohn Kyung-Hee
Kang Sung-Yoon
Yoon Soon-Ho
Choi Young-Hun
Kang Hye-Ryun
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Abstract
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With the development and introduction of advanced medical imaging technology using iodinated contrast media (ICM), ICM related adverse events are rapidly increasing. Both immediate and delayed type hypersensitivity reactions (HSRs) can occur by ICMs. Immediate HSRs can develop as an allergic-like reaction by stimulating mast cells or a chemico-physiological reaction according to ionicity or osmolality of ICM. Immediate HSRs can be classified into mild, moderate, and severe based on the severity. HSRs are infrequent but can be fatal and result in life-threatening situation. Therefore, preparation and training for the prompt management is important. In this review, we dealt with how to manage HSRs to ICM and what to prepare for the high risk patients at the time of re-exposure in order to prevent ICM related HSRs and minimize the risk of fatality.
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KEYWORD
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Contrast media, Hypersensitivity, Premedication, Secondary prevention
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