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KMID : 1011620130290020185
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Korean Journal of Food and Cookey Science
2013 Volume.29 No. 2 p.185 ~ p.192
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Effects of Agarum cribrosum on the Improvements in Treating Constipation and Plasma lipid Profiles
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박성신:Park Sung-Jin
김봄:Kim Bom/김민정:Kim Min-Jeong/김영언:Kim Young-Eon/박성혜:Park Sung-Hye/박태길:Park Tae-Gil
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Abstract
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The present study was conducted to evaluate the effects of Agarum cribrosum on weight change and defecation states in rats with constipation induced by loperamide. Food intake and body weight both decreased in the 5% Agarum cribrosum and loperamide-treated group (SD5) and 10% Agarum cribrosum and loperamide-treated group (SD10), whereas fecal water contents increased by 1.6 and 2.1-fold in the SD5 and SD10 groups, respectively. The concentrations of total-cholesterol, HDL-cholesterol and triglyceride in the sera of the SD5 and SD10 groups were lower than those in the control (C) group. However, the biochemical parameters, GOT (glutamic oxaloacetic transaminase), GPT (glutamic pyruvic transaminase), and glucose levels, were not affected by the level of Agarum cribrosum. In addition, the concentrations of total-cholesterol and triglyceride in the livers of the SD5 and SD10 groups were also lower than those in the control group. The results of the present study demonstrated that Agarum cribrosum might ameliorate constipation symptoms, and lower lipid concentrations in the blood and liver.
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KEYWORD
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Agarum cribrosum, transmit time, loperamide, constipation, fecal weight
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