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KMID : 1022220130020010076
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Clinical Nutrition Research
2013 Volume.2 No. 1 p.76 ~ p.79
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Wheat-Induced Anaphylaxis in Korean Adults: A Report of 6 Cases
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Lee Seung-Eun
Lee Suh-Young
Jo Eun-Jung
Kim Mi-Young
Kim Sae-Hoon
Chang Yoon-Seok
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Abstract
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Wheat is a common cause of food allergy. Wheat-induced anaphylaxis (WIA) and wheat-dependent exercise induced anaphylaxis (WDEIA) are severe forms of immunoglobulin E (IgE) mediated allergic reaction to wheat protein. As the diagnosis of WIA or WDEIA is not easy because of the risk of oral challenge, identification of specific IgE of various wheat proteins is helpful for diagnosis. In Korea, there are only a few reports on WIA in adults. We report six cases of WIA diagnosed on the basis of clinical history and specific IgE of wheat proteins or provocation test. For immunologic evaluation of severe wheat allergy including WIA and WDEIA, it is important to measure specific IgE to each component of wheat including gluten and ω-5 gliadin not just measuring wheat-specific IgE.
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KEYWORD
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Wheat allergy, Anaphylaxis, Immunoglobulin E
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