KMID : 1023519920150010026
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Korean Journal of Veterinary Service 1992 Volume.15 No. 1 p.26 ~ p.31
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Studies on Protective Efficacy of Escherichia coli Vaccines
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Ahn Jae-Moon
Kwak Hak-Koo Kim Hong-Ki
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Abstract
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The oil emulsion and alhydrogel vaccines were prepared from a strain of enterotoxigenic Escherichia coli isolated from calves with diarrhea and their protective efficacy and immunogenicity were tested in Guinea-pigs. Enterotoxigenic Escherichia coli, isolated from calves with diarrhea, has K99 and F4l antigen as 46.2£¥ and 50.9£¥ with 48 and 53 strains respectively out of 104 strains. The protective efficacy of the gel and oil vaccines were 60% and 80% respectively. Agglutinin titers to sera of Guinea-pigs vaccinated with experimental gel and oil vaccines peaked at 5 and 6 weeks after vaccination.
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KEYWORD
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oil emulsion vaccine, alhydrogel vaccine, agglutinin titer, protective efficacy
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