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KMID : 1023519950180030029
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Korean Journal of Veterinary Service
1995 Volume.18 No. 3 p.29 ~ p.35
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Control of parturition time on Pig 4. Effect of prostaglandin F₂α on uterine smooth muscle motility
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Shim Cheol-Soo
Jung Sung-Jin
Lee Yang-Sung
Lim Jong-Ok
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Abstract
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The effects of prostaglandin were investigated on the uterine smooth muscle motility in the pig. The results were summarized as follows : 1. Prostaglandin caused the contraction of the porcine uterine smooth muscle and the contractile responses increased between the concentration of prostaglandine M and M with a dose-dependent manner. 2. The contractile response induced by prostaglandine ( M) was not blocked by pre-treatment with cholinergic receptor blocker, atropine ( M). 3. The contractile response induced by prostaglandine (10 M) was not blocked by pretreament with -adrenergic receptor blocker, phentolamine( M) and -adrenergic receptor blocker, propranolol( M). From these results, it was concluded that the effects of uterine smooth muscle by prostaglandine were only the contraction mediated by prostaglandine TEX>$F_2{\alpha}$ receptor in pig, and that it may not be related to the cholinergic and adrenergic receptor.
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KEYWORD
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Prostaglandin F₂α, uterine, pig
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