KMID : 1023520020250030221
|
|
Korean Journal of Veterinary Service 2002 Volume.25 No. 3 p.221 ~ p.227
|
|
Study on analytical method of residual macrolide antibiotics in livestock products by LC/MS
|
|
Hwang Lae-Hwong
Yun En-Sun Kim Yoen-Joo Kim Dong-Eon Yang Yun-Mo Lee Jung-Hark Lee Byung-Dong
|
|
Abstract
|
|
|
This study was carried out to confirm analytical method of residual macrolides in livestock products by LC/MS. 1. Macrolides were analyzed by LC/MS on XTerra C18/ column with 0.1% TFA(trifluoroacetic acid)-methanol in a gradient mode as mobile phase, and that were identified by positive chemical ionization with selective ion monitoring at 50¢¦1000 mass range. 2. Residual macrolides were extracted from tissue with acetonitrile, and the extract is purified with a Sep-pak C18/ cartridge, and elute macrolides with 0.1M methanolic ammonium acetate. 3. The procedure confirms the presence of each macrolide at 50/kg in spiked sample.
|
|
KEYWORD
|
|
Macrolide antibiotics, LC/MS, Livestock products
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|