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KMID : 1023520110340040403
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Korean Journal of Veterinary Service
2011 Volume.34 No. 4 p.403 ~ p.407
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Spontaneous canine T-cell Lymphosarcoma in a Shih Tzu dog
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Oh Hong-Guen
Chung Yung-Ho
Lee Hyun-A
Hong Sun-Hwa
Kim Ok-Jin
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Abstract
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This study describes a canine lymphosarcoma with a rapid proliferation and recurrence. A 4-year-old, male, Shih Tzu dog was examined for acute swelling mass. The mass had been identified since 3 months ago and enlarged 10×7 cm and located in the right axillary region. The surgical removal was recommended when patient visited veterinarian and the operation was conducted. The removed tumor was 11×8×7 cm and firm, lobulated and white cut surface. Routine screening laboratory test was assessed with blood and radiological analysis. The metastasis sign was not detected on thoracic and abdominal radiography. Blood test revealed decreased lymphocytes. After surgical removal of the mass, microscopic histopathological examination was performed to determine the final diagnosis. Histopathologically, the tumors are characterized by the same histological features, including the presence of neoplastic cellular populations, and lymphocytes infiltration in varying proportions. Also, DNA was extracted and PCR analysis was employed to analyze the origin of tumor cells. T-cell specific nucleic acid fragments were specifically amplified by PCR. On the basis of the laboratory results, the tumor was diagnosed with canine T-cell lymphosarcoma. On the basis of our knowledge, this is the first report of canine T-cell lymphosarcoma in a Shih Tzu dog.
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KEYWORD
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Lymphosarcoma, T-cell, Tumor, Shih Tzu, Canine
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