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KMID : 1023520140370040225
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Korean Journal of Veterinary Service
2014 Volume.37 No. 4 p.225 ~ p.231
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Characterization of cefotaxime-resistant Escherichia coli isolated from wastewater treatment plant in Daegu
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Kim Hwan-Deuk
Park Dae-Hyun
Lee Mi-Ree
Kim Eun-Jeong
Cho Jae-Keun
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Abstract
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In this study, 185 cefotaxime-resistant Escherichia coli were isolated from different stages of a wastewater treatment plant (WWTP) in Daegu in Korea. Among them, 99.5% (184 isolates) originated from raw sewage and 0.5% (1 isolates) from the final effluent. Cefotaxime-resistant E. coli were high resistant to ampicillin, piperacillin, cefazolin, cephalothin, cefachlor and cefamandole (99.5∼100%). About 93% of the cefotaxime-resistant E. coli were extended-spectrum β-lactamases (ESBL)- producing E. coli. The blaTEM+CTX gene was the most predominant of the ESBL genes (72.5%), followed by blaCTX-M (16.2%), blaTEM (8.7%), blaTEM+CTX+SHV (1.1%), blaTEM+SHV, blaTEM+OXA, and blaTEM+CTX+SHV (respectvely 0.5%). Class 1 and 2 integron were found in 49.7% and class 3 integron was not found. All of integron positive isolates were multiresistant (i.e. resistant to four or more antibiotics). Our findings showed WWTP is contaminated with antibiotic resistant bacteria with resistance genes.
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KEYWORD
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WWTP, CTX-resistant E. coli, ESBL genes, Integrons
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