KMID : 1023520150380030199
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Korean Journal of Veterinary Service 2015 Volume.38 No. 3 p.199 ~ p.203
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Malignant mesothelioma of omentum in a dog
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Park Ja-Sil
Min Chang-Woo Kim Ah-Young Lee Eun-Mi Lee Eun-Joo Kang Kyung-Ku Kim Sang-Hyeob Lee Myeong-Mi Sung Soo-Eun Hwang Mee-Yul Kwon Young-Sam Kim Tae-Hwan Jeong Kyu-Shik Kim Jae-Hoon
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Abstract
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An 8-year old intact female poodle was presented to clinics due to abdominal distension, anorexia, and labored breath associated with pleural effusion. Intra-operative findings revealed multiple neoplasm of the greater omentum, involving anterolateral abdominal wall, sterna surface in the pleural cavity and diaphragm. These masses were 0.1¡0.5 cm in diameter and extended to ovaries, pancreas, and serosal surface of stomach. Microscopically, most neoplastic cells had oval nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. In deeper area, neoplastic acinus or glandular structures showed invaginated growth resembling adenocarcinoma. High mitotic figures were observed. By immunohistochemistry, the neoplastic cells were strong positive both cytokeratin and vimentin. The present case described for malignant mesothelioma in a dog. Our findings might be helpful for diagnosis and information and helped the clinics choose the treatment including chemotherapy such as cisplatin.
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KEYWORD
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Dog, Malignant, Mesothelioma, Radiography, Immunohistochemistry
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