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KMID : 1023520170400030209
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Korean Journal of Veterinary Service
2017 Volume.40 No. 3 p.209 ~ p.213
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Detection of atypical porcine pestivirus (APPV) from a case of congenital tremor in Korea
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Kim Seung-Chai
Jeong Chang-Gi
Yoon Seung-Min
Lee Ki-Ho
Yang Myoun-Sik
Kim Bum-Seok
Lee Seung-Yoon
Kang Seog-Jin
Kim Won-Il
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Abstract
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Congenital tremor (CT) is a sporadic neurodegenerative disease reported in suckling piglets worldwide. Since atypical porcine pestivirus (APPV) was first identified in US in 2015, it has also subsequently detected in Europe and China as a causative pathogen for CT in suckling piglets. Three new-born piglets died from severe tremor was submitted to Chonbuk National University-Veterinary Diagnostic Center (CBNU-VDC) and various tissues (lung, lymph node, brain, intestine) were tested with panpestivirus RT-PCR and APPV NS5B-specific RT-PCR. All of the samples were positive by both of the PCR tests and the partial NS5B sequences of APPV were confirmed by sequencing on the PCR products of APPV NS5B-specific RT-PCR. Therefore, we report the first identification of APPV from a case of CT in suckling piglets in Korea.
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KEYWORD
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Pigs, Pestivirus, Congenital tremor, Dancing pig disease, Atypical porcine pestivirus (APPV)
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