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KMID : 1023520170400040227
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Korean Journal of Veterinary Service
2017 Volume.40 No. 4 p.227 ~ p.233
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The change aspects between testosterone and cytokines by castration in Hanwoo cattle
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Kim Seong-Bum
Cho A-Ra
Choi Chang-Yong
Jung Young-Hun
Yoo Jae-Gyu
Kim Eun-Ju
Do Yoon-Jung
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Abstract
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The purpose of this study is to determine the changes of cytokines and immune cells in blood in castrated Hanwoo. The cytokine production and the number of immune cells were determined by collecting blood from jugular vein before castration and on 1, 7, and 28 days then after. Results of the hematological test showed that the number of leukocyte tend to increase after castration, and it significantly decreased on day 7 and day 28 (P＜0.05). Lymphocytes decreased significantly on day 1 and 7 (P ＜0.05), and then recovered as in neutrophils on day 28. The levels of serum testosterone, TNF-a, IL-6, and anti-inflammatory IL-10 significantly decreased (P＜0.05) after castration. There was also a decrease in IL-2, IFN- γ, and IL-4 but showed no significant difference when compared to intact ones. These results suggest that testosterone-deficiency does not affect the number of immune cells in blood, but has a close relationship with cytokine production.
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KEYWORD
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Testosterone, Cytokine, Castration, Hanwoo
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