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KMID : 1023520230460030235
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Korean Journal of Veterinary Service
2023 Volume.46 No. 3 p.235 ~ p.241
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Identification of a norovirus from diarrheic dog in Gwangju, Republic of Korea
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Koh Ba-Ra-Da
Seo Su-Yeon
Choi Ga-Hoi
Yoon Byeong-Cheol
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Abstract
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Noroviruses are a major cause of gastroenteritis in humans and animals worldwide. In 2021, canine norovirus (CNoV) infection was detected at an animal clinic in Gwangju area, South Korea. A semi-nested polymerase chain reaction was developed to amplify a 478 bp fragment of the RdRp gene of CNoV. The phylogenetic analysis of this fragment confirmed the strain to be genogroup IV.2 (Dog/GIV.2/gw/s377/2021/KOR), which exhibited the highest similarity to the feline NoV strain GIV.2/CU081210E/USA/2010 (accession no. NC_045762) with 95.1% nucleotide (nt) identity and 98.7% amino acid (aa) identity. These research findings indicate that the detected norovirus in dogs is genetically similar to a feline-origin norovirus, suggesting easy cross-species transmission among animals.
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KEYWORD
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Norovirus, Dog, Semi-nested PCR, RdRp gene, South Korea
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