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KMID : 1023820150070020166
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The Journal of Advanced Prosthodontics
2015 Volume.7 No. 2 p.166 ~ p.171
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Evaluation of antibacterial activity and osteoblast-like cell viability of TiN, ZrN and (Ti1-xZrx)N coating on titanium
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Ji Min-Kyung
Park Sang-Won
Lee Kwang-Min
Kang In-Chol
Yun Kwi-Dug
Kim Hyun-Seung
Lim Hyun-Pil
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Abstract
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PURPOSE : The aim of this study was to evaluate antibacterial activity and osteoblast-like cell viability according to the ratio of titanium nitride and zirconium nitride coating on commercially pure titanium using an arc ion plating system.
MATERIALS AND METHODS : Polished titanium surfaces were used as controls. Surface topography was observed by scanning electron microscopy, and surface roughness was measured using a two-dimensional contact stylus profilometer. Antibacterial activity was evaluated against Streptococcus mutans and Porphyromonas gingivalis with the colony-forming unit assay. Cell compatibility, mRNA expression, and morphology related to human osteoblast-like cells (MG-63) on the coated specimens were determined by the XTT assay and reverse transcriptase-polymerase chain reaction.
RESULTS : The number of S. mutans colonies on the TiN, ZrN and (Ti1-xZrx)N coated surface decreased significantly compared to those on the non-coated titanium surface (P<0.05).
CONCLUSION : The number of P. gingivalis colonies on all surfaces showed no significant differences. TiN, ZrN and (Ti1-xZrx)N coated titanium showed antibacterial activity against S. mutans related to initial biofilm formation but not P. gingivalis associated with advanced periimplantitis, and did not influence osteoblast-like cell viability.
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KEYWORD
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Periimplantitis, Antibacterial activity, Titanium nitride (TiN), Zirconium nitride (ZrN), Streptococcus mutans, Porphyromonas gingivalis
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