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KMID : 1023820210130020100
The Journal of Advanced Prosthodontics
2021 Volume.13 No. 2 p.100 ~ p.106
Evaluation of antibacterial activity against Candida albicans according to the dosage of various denture cleansers
Bae Cha-Hwan

Lim Yun-Kyong
Kook Joong-Ki
Son Mee-Kyung
Heo Yu-Ri
Abstract
PURPOSE: The purpose of this study is to compare the antibacterial activity of currently purchasable denture cleansers against Candida albicans.

MATERIALS AND METHODS: This study used tablet-type denture cleansers, Polident¢ç, Coolingdent¢ç and Fittydent¢ç, along with liquid denture cleansers, Hexamedine¢ç, Listerine¢ç and Apple vinegar¢ç. The antibacterial activities of denture cleansers were evaluated based on the number of C. albicans and concentrations of the denture cleansers.

RESULTS: In the 0.5 ¡¿ 106 cfu/ml culture medium, the C. albicans' death rate of Polident¢ç was significantly lower than those of Fittydent¢ç, Hexamedine¢ç, Listerine¢ç, and Apple vinegar¢ç(P<.05). In the 0.5 ¡¿ 107 cfu/, the C. albicans' death rates of Polident¢ç and Coolingdent¢ç were significantly lower than those of Fittydent¢ç, Hexamedine¢ç, Listerine¢ç and Apple vinegar¢ç(P<.05). The C. albicans' death rates of Polident¢ç and Coolingdent¢ç were significantly decreased at 0.02 g and 0.01 g. The C. albicans' death rate of Fittydent¢ç was significantly decreased at 0.005 g (P<.05). The C. albicans' death rate of Hexamedine¢ç was significantly decreased at 1/16 dilution. The C. albicans' death rate of Listerine¢ç was decreased at 1/8 dilution, and the antibacterial activity of Apple vinegar¢ç was decreased at 1/4 dilution (P<.05).

CONCLUSION: As the number of C. albicans increased, the antibacterial activities of the denture cleansers decrease. In the tablet-type denture cleanser, all denture cleansers showed 100% C. albicans' death rate when used at a dose of 1 tablet. One denture cleanser showed the same antibacterial effect with only 1/3 of a tablet. In the liquid type denture cleanser, the level of dilution required was different for each denture cleanser.
KEYWORD
Antibacterial activity, C. albicans, Liquid denture cleanser, Tablet type denture cleanser
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