KMID : 1024620030230010080
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Food Science of Animal Resources 2003 Volume.23 No. 1 p.80 ~ p.85
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Antimicrobial and Antitumoral Activities of Candida kefyr TEP 7 Isolated from Tibetan Fermented Milk
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Yoon Wan-Ho
Na Young-Mi Kim Chang-Han
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Abstract
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This study was carried out to investigate antimicrobial and antitumoral activities of Candida kefyr TFP7 isolated from Tibetan fermented milk Strains of TFP1¡10 were isolated from Tibetan fermented milk by agar diffusion method using potato dextrose agar(PDA). Antimicrobial activities were examined against 18 microorganisms of food-related bacteria, yeast, algae, fungi and actinomycetes isolated from soil. Antitumor activities were examined against 9 human tumor cell lines. Strains of TFP2¡10 showed strong antimicrobial activities against Micrococcus luteus ATCC l1880, and strains of TFP6¡10 to actinomycetes, Streptomyces murinus JCM 4333. In antitumor test, all isolated strains(TEP1¡10) showed the growth inhibition of SNU-5 and SW-534 by 60% and 70%, respectively. Among those, the strain TFP7 showed the most antitumor activity, which was 77.5% for SNU-5 and 76.5% for SW-534. The strain was identified as Candida kefyr by use of API 20C AUX kit and scanning electron micrograph.
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KEYWORD
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antimicrobial activity, antitumor activity, candida kefyr, tibetan fermented milk
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