KMID : 1024620220420010186
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Food Science of Animal Resources 2022 Volume.42 No. 1 p.186 ~ p.196
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Effect of Flutriafol Exposure on Residue Characteristics in Pig Muscle and Fat Tissue
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Jeong Jin-Young
Kim Byeong-Hyeon Ji Sang-Yun Baek Youl-Chang Kim Min-Ji Park Seol-Hwa Jung Hyun-Jung
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Abstract
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This study investigated the effect of exposure to flutriafol based on residues in pigs. Pigs were exposed to different concentrations (0.313, 0.625, 3.125, 6.25, and 12.5 mg/kg bw/d, n=20) for 4 wk in different treatment groups. Serum biochemical analysis, residue levels, and histological analysis were conducted using the VetTest chemistry analyzer, liquid chromatography mass spectrometry, and Masson's trichrome staining, respectively. The body weight (initial and final) was not significantly different between groups. Parameters such as creatinine, blood urea nitrogen, alanine aminotransferase, and lipase levels were significantly different as compared to the control group. Flutriafol increased the residue limits in individual tissue of the pigs in a dose dependent manner. Flutriafol exposures indicated the presence of fibrosis, as confirmed from Masson's trichrome staining. These results suggest that flutriafol affects the morphology and serum levels in pigs. The dietary flutriafol levels can provide a basis for maximum residue limits and food safety for pork and related products.
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KEYWORD
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pig, flutriafol, fibrosis
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