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KMID : 1025520080500030301
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Journal of Animal Science and Technology
2008 Volume.50 No. 3 p.301 ~ p.308
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Genetic Polymorphisms of MYL2 and ADCYAP1R1 Genes and Their Association With Carcass Traits in Finished Pigs
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Han Sang-Hyun
Shin Kwang-Yun
Lee Sung-Soo
Ko Moon-Suck
Seong Pil-Nam
Kwon Ki-Baek
Cho In-Cheol
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Abstract
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DNA variation of MYL2 intron 5 A345G and ADCYAP1R1 intron 2 A337G were investigated for carcass trait association in finished pigs. Three genotypes(two homozygotes and their heterozygote) were found at 10.6% AA, 45.6% AG and 43.8% GG in MYL2 and 60.5% AA, 34.6% AG, and 22.2% GG for ADCYAP1R1. In finished pig population, individuals containing genotype G- of MYL2 had significantly heavier carcass weight by more than 2.4 kg and thicker backfat thickness by more than 1.3 mm than those of AA homozygous pigs(p<0.05). No significant difference was found in other traits tested in this study such as marbling score, meat color, texture, moisture and separation score(p>0.05). The ADCYAP1R1 intron 2 377GG homozygotes showed coarse texture, i.e., meat quality was inferior than those of AG and AA genotypes, and the moisture level of homozygote AA was higher than those of AG and GG genotypes(p<0.05). The other carcass traits were not significantly associated with ADCYAP1R1 genotypes(p>0.05). The genetic polymorphism of MYL2 and ADCYAP1R1 genes affected the carcass traits in finished pig population. Further studies to explain the association between genetic variations and their phenotypic effects including economic traits in pigs are required including critical mutation in both genes through molecular approaches.
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KEYWORD
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Genetic polymorphism, Myl2, ADCYAP1R1, Carcass trait, Pig
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