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KMID : 1025720230420020024
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Journal of Dental Implant Research
2023 Volume.42 No. 2 p.24 ~ p.29
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Clinical outcomes of micro-sized autogenous demineralized dentin matrix for periodontal bone defects: A case report
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Park Tae-Hyeong
Ku Jeong-Kui
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Abstract
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Periodontal disease is a common oral health problem that can lead to tooth loss. The treatment of periodontal defects involves a resection and regenerative surgery. Autogenous demineralized dentin matrix (auto-DDM), a bone substitute derived from extracted teeth, has shown promise in regenerative periodontal surgery. This case report introduces the clinical outcomes of micro-sized DDM for periodontal bone defects. This case report presents the clinical outcomes of microparticle-sized auto-DDM (<200 μm) for treating periodontal bone defects. A 44-year-old woman with premolar mobility underwent a bone graft for an auto-DDM. The results revealed improved alveolar bone stability and reduced periodontitis symptoms. A radiographic examination revealed increased radio-opacity in the defective area, indicating bone regeneration. Fine-sized auto-DDM particles facilitated the release of growth factors and promoted osteoinductivity. The absence of a barrier membrane did not impede the successful outcomes. Auto-DDM can be used as a biomaterial for periodontal regeneration by delivering endogenous growth factors. Further prospective studies and histological analyses will be needed to validate its effectiveness in regenerating the periodontal ligament and alveolar bone.
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KEYWORD
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Periodontitis, Demineralized dentin matrix, Bone regeneration, Dentistry
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