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KMID : 1030220140150030134
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Journal of Korean Diabetes
2014 Volume.15 No. 3 p.134 ~ p.141
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Management of Diabetes in Organ Transplant Patients
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Yun Yu-Jung
Kang Eun-Seok
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Abstract
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New onset diabetes after transplantation (NODAT) is a common complication after solid-organ transplantation and is associated with increased cardiovascular morbidity, mortality, and graft loss. The risk factors for NODAT include older age, ethnicity, genetic factors,obesity, family history of diabetes, hepatitis C virus infection, and immunosuppressant use (corticosteroids, calcineurin inhibitors, and mTOR inhibitor). Management of NODAT must be considered at the pre-transplantation stage in order to properly screen high-risk patients. Although NODAT management is similar to that of general type 2 diabetes, some specific considerations must be made in NODAT management, including the interactions between anti-diabetes medication and immunosuppressive agents.
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KEYWORD
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Diabetes mellitus, Organ transplantation, Risk factors, Diagnosis, Management
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