KMID : 1031120140040020082
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Journal of Epilepsy Research 2014 Volume.4 No. 2 p.82 ~ p.84
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Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
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Roh Sook-Young
Jang Hyun-Soon Jeong Eun-Hye Kim Byung-Su Sunwoo Moon-Kyung
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Abstract
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Encephalopathy resulting from the administration of levetiracetam (LEV) is a rare occurrence. We experienced a patient receiving LEV treated with valproic acid (VPA) for partial seizures with secondary generalization, following which she developed hyperammonemic encephalopathy and showed complete recovery after the drug was withdrawan. LEV is able to promote hyperammonemic encephalopathy when added to VPA.
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KEYWORD
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Valproic acid, Hyperammonemic encephalopathy, Levetiracetam
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