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KMID : 1033220140040020073
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Journal of Acute Care Surgery
2014 Volume.4 No. 2 p.73 ~ p.78
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Myoglobin as a Prognostic Factor in Trauma Patients
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Yeom Ji-Woong
Park Oh-Hyun
Kang Wu-Seong
Kim Jung-Chul
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Abstract
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Purpose: To describe the association of serum myoglobin and creatine kinase (CK) with prognosis in trauma patients.
Methods: We evaluated 108 trauma patients older than age 15 years who received treatment in the Department of Trauma Surgery from January 2012 to December 2012. Myoglobin and CK serum levels were measured during the week after injury.
Results: The average age of the 108 patients (80 [74.1%] men and 28 [25.9%] women) was 49.8 years. Sixteen (14.8%) developed complications and eight (50.0%) developed acute kidney injury (AKI). All patients with AKI underwent hemodialysis, and six died. Higher serum levels of myoglobin and CK were associated with AKI. Twelve patients died during the study period, and myoglobin and CK serum levels were higher in non-survivors. Of these two factors, myoglobin serum level was independently predictive of death.
Conclusion: In trauma patients, higher serum levels of myoglobin and CK were found to be associated with AKI and death. Higher serum levels of myoglobin were influential for predicting death.
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KEYWORD
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Wounds and injuries, Myoglobin, Creatine kinase, Acute kidney injury
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