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KMID : 1035420210090030155
Journal of The Korean Society of Integrative Medicine
2021 Volume.9 No. 3 p.155 ~ p.164
Effects of Transcranial Direct Current Stimulation and Virtual Reality Program Application on the Cognition and Depression of Mild Cognitive Impairment Patients
Kim Ko-Un

Kim Bo-Ra
An Tae-Gyu
Abstract
Purpose : The purpose of this study is to investigate the effects of transcranial direct current stimulation and virtual reality program application on cognition and depression of patients with mild cognitive impairment, and to find an intervention method that can enhance active participation of patients with mild cognitive impairment.

Methods : This study divided 50 mild cognitive impairment patients into a treatment group (25 patients) and a control group (25 patients). The treatment group was applied with a transcranial direct current stimulation and a virtual reality program, while the control group received a placebo transcranial direct current stimulation and a virtual reality program. Both groups received five 30-minute sessions per week (one session per day) for six weeks (total of 30 sessions). NCSE was used to evaluate cognitive functions before and after treatment intervention. Moreover, K-BDI was conducted to examine depression.

Results : As a result of the intervention, the cognitive function of both groups significantly (p<0.05) improved, and the depression of both groups significantly (p<0.05) decreased. Moreover, the changes in cognitive functions and depression were significantly between the two groups (p<0.05).

Conclusion : The results showed that the application of the transcranial direct current stimulation and virtual reality program significantly improved the cognitive function of mild cognitive impairment patients and decreased the depression of them. Therefore, it could be concluded that the transcranial DC current stimulation and virtual reality program was an intervention method positively affecting the cognitive function and depression of mild cognitive impairment patients.
KEYWORD
Transcranial direct current stimulation, virtual reality program, cognitive function, depression, and mild cognitive impairment
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