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KMID : 1035620220100020123
Allergy Asthma & Respiratory Disease
2022 Volume.10 No. 2 p.123 ~ p.126
A case of food-induced acute pancreatitis in a child with egg white allergy
Lee Ye-Seul

Hwang Ji-Hoon
Kim Su-Kyung
Kim Mi-Jin
Jeon Tae-Yeon
Kim Ji-Hyun
Ahn Kang-Mo
Kim Ji-Won
Abstract
Acute pancreatitis (AP) rarely occurs in association with food allergy (FA), and the mechanism is not clearly explored. We herein report a rare case of egg protein-induced AP. A 5-year-old girl was brought to the hospital because of tongue pruritus and an increased level of egg white-specific immunoglobulin E. During an oral food challenge, she developed hives, abdominal pain and vomiting after ingestion of a cumulative of 610 mg of boiled egg white (70 mg of protein). After management with intramuscular injection of epinephrine and orally administered prednisolone and levocetirizine, her skin symptoms improved. The next day, blood tests showed elevated levels of amylase and lipase, and computed tomography revealed a swollen pancreas with a low-attenuated necrotic portion. She was diagnosed with AP and treated with food restriction, intravenous methylprednisolone and gabexate mesilate. The serum levels of amylase and lipase were reduced to normal levels on day 5 and her symptoms completely resolved on day 10. A suspicion of food-induced AP is required for correct diagnosis and proper management in children with FA when they manifest severe abdominal pain.
KEYWORD
Food hypersensitivity, Egg hypersensitivity, Pancreatitis
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