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KMID : 1036420090020010011
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대한치의학회 영문학회지
2009 Volume.2 No. 1 p.11 ~ p.18
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Cytotoxicity of Root Canal Sealers Containing Calcium Hydroxide
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Kim In-Geol
Han Se-Hee
Cho Young-Gon
Lee Sang-Bae
Kim Kwang-Mahn
Kim Kyoung-Nam
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Abstract
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The purpose of this study was to investigate the possibility to reduce the toxicity of oil based root canal sealers containing calcium hydroxide using MTT & agar overlay assays. Thus some formulations of traditional root canal sealers were replaced with oil-soluble solvents and experimental root canal sealers manufactured. In MTT assay, Cell viability of all experimental sealers in addition with oil soluble solvents were observed significantly higher than both control groups, especially according to replace zinc and/or calcium ion components. Also agar overlay assay was appeared moderate to no cell responses into modifying both zinc and/or calcium ion components and oil soluble solvent weight. Authors found the reducing effect of cell toxicity through significant role of oil soluble solvent factor into root canal sealer containing calcium hydroxide.
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KEYWORD
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cytotoxicity, endodontic sealer, calcium hydroxide, oil based, MTT, agar overlay
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