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KMID : 1036420110040020039
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대한치의학회 영문학회지
2011 Volume.4 No. 2 p.39 ~ p.45
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The Role of Collagen Membrane as a Scaffold of Etchant for Regional Acceleratory Phenomenon
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Shin Seung-Woo
Pyo Sung-Woon
Bae Sun-Sook
Lee Pil-Woo
Heo Hyun-A
Lee Won
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Abstract
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Purpose: The goal of this research is to find the role of collagen membrane, which can reduce physical damage, as a scaffold for possible alternative to the corticotomy which causes Regional Acceleratory Phenomenon (RAP).
Materials and Methods: The experiments were carried out on 12 New Zealand white rabbits, approximately 3.5 kg in bodyweight. We made an incision on the skin of the mandibular border and applied 37% phosphoric acid and collagen membrane to the mandibular bone surface of the first group (experimental group), and only phosphoric acid to the second group (control group). After 3 days, 1 week, and 2 weeks, 4 rabbits each were sacrificed and specimens were obtained. Each specimen was stained by H&E and Tartrate-resistant acid phosphatase (TRAP), and histological changes were observed by light microscope.
Results: The demineralization of the experimental group was weak compared to the control group. It also showed a gradual increase of demineralization (after 3 days, 1 week, and 2 weeks) and the control group showed more extensive demineralization than the experimental group.
Conclusion: This study demonstrates the amount of demineralization as a result of using phosphoric acid, and as time went by, demineralization increased. The absorbable collagen membrane was used as a scaffold to increase bone demineralization effect and prevent dispersion to adjacent tissues, but rather the amount of bone demineralization decreased. Therefore, the role of collagen membrane as a scaffold for RAP was weak.
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KEYWORD
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Corticotomy, Regional acceleratory phenomenon, Demineralization, Collagen membrane
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