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KMID : 1036820140190040551
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Communication Sciences & Disorders
2014 Volume.19 No. 4 p.551 ~ p.557
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Characteristics of Dysarthria and Cognitive Functions in Patients with Parkinson’s Disease and Parkinson-plus Syndrome
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Kim Ja-Young
Chung Sun-Ju
Lee Jae-Hong
Kwon Mi-Seon
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Abstract
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Objectives: This study was to investigate the characteristics of dysarthria and cognitive ability of patients with Parkinson’s disease and Parkinson-plus syndrome to find the key components that can differentiate these diseases.
Methods: Forty-one patients (11 patients with idiopathic Parkinson’s disease [IPD], 10 with multiple systems atrophy with predominant cerebellar ataxia [MSA-c], 10 with multiple systems atrophy with predominant Parkinsonism [MSA-p], and 10 with progressive supranuclear palsy [PSP]) participated. After controlling the motor ability in rigidity, bradykinesia, and ataxia in the Unified Parkinson’s Disease Rating Scale of 4 groups, dysarthria was assessed by performing tasks of prolonged phonation, diadochokinesis, and connected speech. In addition, cognitive function was measured by the Korean version of the Montreal Cognitive Assessment.
Results: The age, education level, disease duration, and motor ability of patients were not significantly different. However, analysis of motor ability showed significant (p<.05) differences between IPD-MSA-p, and MSA-c-MSA-p group for rigidity, and between IPD-MSA-c, MSA-c-MSA-p, and MSA-p-PSP group for ataxia. There was no significant difference for bradykinesia. In addition, dysarthria evaluation showed that the hypokinetic component was more frequently observed in the IPD and MSA-p than the MSA-c group and the ataxic component was greater in the MSA-c than other groups. Moreover, cognitive ability was significantly (p<.05) more impaired in patients with PSP than the IPD & MSA-c groups.
Conclusion: The characteristics of dysarthria and cognitive deficits may serve as useful factors in distinguishing IPD, MSA-c, MSA-p, and PSP. Further studies including large numbers of patients are warranted to confirm these results.
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KEYWORD
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Parkinson’s disease, Parkinson-plus syndrome, Dysarthria, Cognitive function, Differentiate diseases
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