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KMID : 1038820200230020154
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Pediatric Gastroenterology, Hepatology & Nutrition
2020 Volume.23 No. 2 p.154 ~ p.162
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Cow's Milk-Related Symptom Score in Presumed Healthy Polish Infants Aged 0?6 Months
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Bigorajska Karolina
Filipiak Zuzanna
Winiarska Paulina
Adamiec Anita
Trent Bogumiła
Vandenplas Yvan
Ruszczynski Marek
Szajewska Hania
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Abstract
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Purpose: The Cow's Milk-related Symptom Score (CoMiSS™), which considers crying, regurgitation, stools, skin and respiratory symptoms, was developed as an awareness tool for evaluating cow's milk-related symptoms. The scoring ranges from 0 to 33. A score ≥12 was proposed as being likely cow's milk-related and suggestive of allergy to cow's milk. This study aimed to determine the age-related CoMiSS™ values in presumed healthy infants in Poland.
Methods: This was a cross-sectional study conducted in well-child clinics in two locations. Parents of the presumed healthy infants aged ≤6 months were approached during a routine checkup/vaccination visit. The exclusion criteria were as follows: presence of acute or chronic diseases, preterm delivery, treatment with therapeutic formula, and use of any food supplements (except vitamins) or medications.
Results: Data from 226 infants were obtained (median age [Q1?Q3], 4 months [3?4]). The overall median (Q1?Q3) and mean (standard deviation) CoMiSS™ values were 4 (2?7) and 4.7 (3.5), respectively. The 95th percentile was 11. Scores on some, albeit not all, components of the CoMiSS™ significantly differed between age groups (crying, stools) or feeding type groups (stools and skin symptoms). Eleven children (4.9%) scored ≥12.
Conclusion: This study adds to earlier age-related CoMiSS™ data by providing CoMiSS™ values in presumed healthy infants in Poland.
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KEYWORD
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Infant, Milk, Food allergy, Food hypersensitivity
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