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KMID : 1039120230120010080
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Clinical and Experimental Vaccine Research
2023 Volume.12 No. 1 p.80 ~ p.81
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Psoriasis flares after COVID-19 vaccination: adherence to biologic therapy reduces psoriasis exacerbations: a case-control study
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Martina Burlando
Astrid Herzum
Emanuele Cozzani
Aurora Parodi
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Abstract
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This study aimed to evaluate if patients under biologics have a lower risk of psoriasis flares after coronavirus disease 2019 (COVID-19) vaccination than other psoriatic patients. Of 322 recently vaccinated patients admitted for psoriasis at the Dermatological Psoriasis Unit during January and February 2022, 316 (98%) had no psoriasis flares after COVID-19 vaccination (79% under biologic treatment, 21% not biologically treated) and 6 (2%) presented psoriasis flares after COVID-19 vaccination (33.3% under biologic treatment, 66.6% not biologically treated). Overall, psoriasis patients under biologic treatment, developed fewer psoriasis flares after COVID-19 vaccination (33.3%), than patients not under biologic treatment (66.6%) (p=0.0207; Fisher’s exact test).
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KEYWORD
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COVID-19 vaccination, Psoriasis flare, Brodalumab, Guselkumab, Biological products, Biologic therapy
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