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KMID : 1039220230330010034
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Journal of Korean Society of Occupational and Environmental Hygiene
2023 Volume.33 No. 1 p.34 ~ p.39
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A Study on the Safety of Alcohol-based Hand Sanitizers
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Jung Sun-Ok
Lee Chun-Yeong
Ryu Hoe-Jin
Choi Hee-Jin
Kim Ji-Young
Choi Chae-Man
Hwang In-Sook
Shin Yong-Seung
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Abstract
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Objectives: In this study, the safety of alcohol-based hand sanitizers (ABHSs) for quasi-drugs and cosmetics was investigated by analyzing the ethanol content, which is an active ingredient with a sterilizing effect, and methanol, which is toxic.
Methods: Forty-one ABHSs were purchased at large supermarkets and online stores. Ethanol quantification was performed by gas chromatography-flame ionization detector, and methanol quantification was performed by headspace-gas chromatography-mass spectrometry.
Results: The ethanol content of ABHS in quasi-drugs was 49.6-67.8%, which was suitable for standard manufacturing
procedures for external disinfectants, and the ethanol content of ABHS in cosmetics was 9.1-61.3%. The methanol content of ABHS in quasi-drugs ranged from not detected(N.D.)-131.8 ppm, which was suitable for the methanol detection standard of ethanol raw materials in the Korean Pharmacopoeia. The methanol content of ABHS in cosmetics was 23.4-859.7 ppm, which was suitable for the detection limit of methanol in cosmetics.
Conclusions: The ethanol and methanol content of ABHS was judged to be safe. When selecting an ABHS to be used for sterilization, it seems necessary to check the content of ethanol, an active ingredient, and use it according to its intended purpose.
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KEYWORD
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ABHS, COVID-19, ethanol, methanol
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